| Bounce | Ctrl-b |
| Check for new mail | Ctrl-m |
| Compose new message | Ctrl-n |
| Execute custom button function | Ctrl-{Button number} For example, to execute the function associated with custom button number 2 use Ctrl-2 (for button 10 use Ctrl-0) |
| Delete message | Ctrl-d |
| Find message | Ctrl-f |
| Forward message | Ctrl-w |
| Jump to next window | Ctrl-F6 |
| Mark Unread: | Ctrl-[ |
| Mark Read: | Ctrl-] |
| Minimize Poco to the taskbar | Alt+Space, n |
| Open context window | Menu key ( ) |
| Print current message | Ctrl-p |
| Reply to a message | Ctrl-r |
| Reply to all: | Ctrl-Shift-R |
| Save message as a text file | Ctrl-s |
| Scroll message down (moves to next topic when at end of message in threaded mode or to next message when not threaded) | Space bar |
| Scroll message up (moves to previous topic when at end of message in threaded mode or to previous message when not threaded) | Shift space |
| Send queued messages | Ctrl-y |
| Start a new message | Ctrl-n |
| Toggle download images setting | Shift F10 |
| Toggle "Last Check Mail Status" and message preview window | Ctrl-F12 |
| View Messages on Server | Ctrl-K |
| View Next Message: | Alt-RightArrow |
| View Previous Message: | Alt-LeftArrow |